Description
Product Characteristics: FUNCTION: Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. Binding of AP180 to clathrin triskelia induces their assembly into 60-70 nm coats. SUBCELLULAR LOCATION: Cell membrane. Membrane âÄ° coated pit, Peripheral membrane protein, Cytoplasmic side. Note: Component of the coat surrounding the cytoplasmic face of coated vesicles in the plasma membrane,SNAP & SNARES,Clathrin coat assembly protein AP180, Clathrin coat-associated protein AP180, 91 kDa synaptosomal-associated protein, SNAP91
Target Information: plays a role in clathrin-dependent assembly of synaptic vesicles at the presynaptic terminal